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Pragmatic trials are those that are designed to provide information for the real-world practice of clinical. They are typically characterized by a focus on practical aspects of the research design, like the recruitment and consent process in adherence, as well as the use of routinely available equipment.
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Another example of a trial that is pragmatic is the Home Blood Pressure Management (HBPM) study, which utilized various investigators and had participants from different geographic areas. This kind of heterogeneity, which is vital for pragmatic trials to be reliable and lessen the chance of bias, is also necessary. However, too much heterogeneity, can cause problems with the design of the trial.
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Legality
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The goal of pragmatic trials is to mimic real-life scenarios and gain maximum credibility externally. Usually, they are commissioned by policymakers and practitioners in order to inform their decisions. They can also be used to assess the causal relationship between an intervention and its results. However, they should not be used as a substitute for the use of explanation trials.
The idea of pragmatism is controversial, and there are questions about whether pragmatic trials can replace tests for explanations or if they should serve as an addition to them. Schwartz and Lellouch1 made an distinction between explanation-based studies, which prove a physiological hypothesis or clinical hypothesis, and pragmatic trials, that inform policy and practice decision-making. They also proposed the framework for pragmatic trials, which they called PRECIS.2 This tool sought to define the elements of a practical trial that include the recruitment process, the design and implementation of the intervention, as well as follow-up.
There is a positive increase in the number pragmatic trials that have been published. A recent Medline search using the words pragmatic and naturalistic, which was restricted to randomised controlled trials (RCTs) returned 34 articles. They are displayed in red on Figure 2. 프라그마틱 사이트 indicates that the health sciences community has become more aware of the importance of pragmatism. It is important to keep in mind that the majority were conducted in primary-care settings.